Bioinformatics Links Directory : Sequence PolymorphismsLinks to various sequence polymorphism databases and resources concerning SNPs, short deletion, and insertion polymorphisms.HGVbase- (Found July 2, 2008 ) Human Genome Variation database - curated; attempt to summarize all known sequence variations in the human genome, to facilitate research into how genotypes affect common diseases, drug responses, and other complex phenotypes.http://hgvbase.cgb.ki.se/ International HapMap Project- (Found July 2, 2008 ) The haplotype map, or HapMap, is a tool that will allow researchers to find genes and genetic variations that affect health and disease.http://www.nhgri.nih.gov/10001688 ISTECH SNPAnalyzer- (Found July 2, 2008 ) ISTECH SNPAnalyzer is a tool for the statistical analysis of SNP data that includes Hardy Weinberg equilibrium (HWE), haplotype estimation, linkage disequilibrium (LD), and QTL analyses. Registration required; some browser requirements and set-up necessary.http://istech21.com/en/service/snp_a01_in.html MutDB- (Found July 2, 2008 ) MutDB is a database that associates protein structural information with mutations and polymorphisms in gene sequences. The data is derived from dbSNP and Swiss-Prot, and can be browsed by gene name or searched by keyword or by various identifiers.http://www.mutdb.org/ nsSNPAnalyzer- (Found July 2, 2008 ) nsSNPAnalyzer is a tool to predict whether a nonsynonymous single nucleotide polymorphism (nsSNP) is phenotypically neutral or disease associated.http://snpanalyzer.utmem.edu/ ORegAnno- (Found July 2, 2008 ) The Open REGulatory ANNOtation database (ORegAnno) is a collection of literature-curated regulatory regions, transcription factor binding sites (TFBS) and regulatory mutations.http://www.oreganno.org The SNP Consortium- (Found July 2, 2008 ) Non-profit foundation whose mission is to develop up to 300,000 SNPs distributed evenly throughout the human genome and to make this information available to the public without intellectual property restrictions.http://snp.cshl.org/ |