Bioinformatics Links Directory : Health and Disease

Resources in this section encompass genomic research related to human health and disease.

GeneCards - (Found June 19, 2008 )

Database of human genes, their products, and involvement in diseases; free for non-commercial use, but users should also read the Terms of Use for this site.
http://www.genecards.org/

G2D - (Found June 19, 2008 )

G2D (Candidate Genes to Inherited Diseases) scans a human genomic region for genes related to an inherited disease. The G2D server also presents precomputed candidate genes for more than 600 genetically inherited diseases that have been mapped onto chromosomal regions without assignment of a particular gene.
http://www.ogic.ca/projects/g2d_2/

FluGenome - (Found June 19, 2008 )

FluGenome is a tool for determining lineages and genotypes of influenza A viruses.
http://www.flugenome.org/

DyNAVacS - (Found June 19, 2008 )

DyNAVacS is a tool for designing DNA vaccines that includes steps for chosing a suitable expression vector, ensuring optimal expression by codon optimization, engineering CpG motifs for enhancing immune responses, and providing additional sequence signals for efficient translation. It also allows includes restriction enzyme mapping and design of primers spanning user specified sequences.
http://202.54.26.221/dynavac/

DTFAM - (Found June 19, 2008 )

Dragon TF Association Miner (DTFAM) is text-mining tool which takes Pubmed abstractssummaries as input and reports potential associations between transcription factors and diseasesGO ontologies. The user can also provide a PubMed query directly to DTFAM and its output will be analysed when the search has completed. There is a limit of 5000 abstracts per session.
http://research.i2r.a-star.edu.sg/DRAGON/TFAM_v2/index.html

CARGO - (Found June 19, 2008 )

CARGO (Cancer And Related Genes Online) is a portal that uses widgets to allow users to mine literature using iHOP, retrieve disease information from OMIM, visualize 3D SNPs, query protein interactions, and view summarized gene annotation information for cancer related genes in human.
http://bioinfo.cnio.es/cargo/cargo.html

CanPredict - (Found June 19, 2008 )

CanPredict uses a combination of computational methods to predict whether specific sequence changes in a protein are likely to be cancer-associated mutations.
http://www.cgl.ucsf.edu/Research/genentech/canpredict/

Cancer Genome Anatomy Project - (Found June 19, 2008 )

Goal is to determine the gene expression profiles of normal, precancer, and cancer cells; resources for human and mouse include ESTs, gene expression patterns, SNPs, cluster assemblies, cytogenetic information, and tools to query and analyze the data.
http://cgap.nci.nih.gov/

TOM - (Found June 19, 2008 )

Transcriptomics of OMIM (TOM) searches for candidate disease genes using user supplied genomic loci. Candidate disease genes are then prioritized using co-expression patterns from public gene expression datasets and functional gene ontology annotations.
http://www-micrel.deis.unibo.it/~tom/