Endocrinology News From Medical News TodayLatest Endocrinology News From Medical News Today.Amicus Therapeutics Announces Successful Completion Of End Of Phase 2 Meeting With FDA For Amigal In Fabry Disease- August 5, 2008 Amicus Therapeutics (Nasdaq: FOLD), a biopharmaceutical company developing small molecule, orally-administered pharmacological chaperones for the treatment of human genetic diseases, announced that it has successfully completed an End of Phase 2 meeting for Amigal(TM) with the U.S. Food and Drug Administration (FDA).http://www.medicalnewstoday.com/articles/117188.php 5-LOXIN(R) Proven To Reduce The Symptoms Of Osteoarthritis In New Human Study Published In Arthritis Research And Therapy- August 4, 2008 PL Thomas (PLT), in alliance with Laila Nutraceuticals, India, jointly announced the publication of a new study using their exclusive dietary supplement ingredient, 5-LOXIN. In the study, 5-LOXIN supplementation conferred clinically and statistically significant improvements in pain scores and physical function scores in OA patients at doses of 100mg and 250mg daily.http://www.medicalnewstoday.com/articles/117080.php New Panel Of Mice Helps Predict How Drugs Are Broken Down In Humans- August 4, 2008 Humans express several proteins that breakdown the synthetic chemicals and drugs (collectively known as xenobiotics) that we ingest or are administered. Expression of these proteins is itself regulated by the xenobiotic-sensing proteins PXR and CAR. Developing animal models to determine the relative importance of PXR and CAR for humans to breakdown a specific drug has been difficult because the human and animal proteins sense different xenobiotics.http://www.medicalnewstoday.com/articles/117044.php Growth Hormone Reduces Fat In HIV Patients With Abdominal Obesity- August 4, 2008 According to an article published on August 6 in a special HIVAIDS issue of JAMA, a low-dose hormone treatment for human immunodeficiency virus (HIV)-infected patients who have treatment-related abdominal obesity and growth hormone deficiency resulted in gains in fat and blood pressure measurements. However, Steven Grinspoon, M.D. (Massachusetts General Hospital, Boston) and colleagues also found that the treatment worsened glucose levels.http://www.medicalnewstoday.com/articles/116987.php Brain Regulates Free Radicals, Plays Key Role In Appetite- August 3, 2008 Researchers at Yale School of Medicine have found the brain's appetite center uses fat for fuel by involving oxygen free radicals - molecules associated with aging and neurodegeneration. The findings, reported in the journal Nature, suggest that antioxidants could play a role in weight control.http://www.medicalnewstoday.com/articles/116828.php Brain And Reproductive Development Affected By Compounds From Soy, New Study Shows- August 2, 2008 Two hormone-like compounds linked to the consumption of soy-based foods can cause irreversible changes in the structure of the brain, resulting in early-onset puberty and symptoms of advanced menopause in research animals, according to a new study by researchers at North Carolina State University. The study is a breakthrough in determining how these compounds can cause reproductive health problems, as well as in providing a key building block for how to treat these problems.http://www.medicalnewstoday.com/articles/116962.php |