Malaria Journal - Most viewed articlesMost viewed articles in last 30 days from Malaria Journal (ISSN 1475-2875) published by BioMed CentralAcute pancreatitis and subdural haematoma in a patient with severe falciparum malaria: Case report and review of literature- May 30, 2008 Plasmodium falciparum infection is known to be associated with a spectrum of systemic complications ranging from mild and self-limiting to life-threatening. This case report illustrates a patient who had a protracted course in hospital due to several rare complications of falciparum malaria. A 21-year old man presented with a five-day history of high-grade fever, jaundice and abdominal pain and a two-day history of altered conscious state. A diagnosis of severe falciparum malaria was made based.http://www.malariajournal.com/content/7/1/97 Plasmodium vivax trophozoites insensitive to chloroquine- May 27, 2008 Background: Plasmodium vivax is a major cause of malaria and is still primarily treated with chloroquine. Chloroquine inhibits the polymerization of haem to inert haemozoin. Free haem monomers are thought to catalyze oxidative damage to the Plasmodium spp. trophozoite, the stage when haemoglobin catabolism is maximal. However preliminary in vitro observations on P. vivax clinical isolates suggest that only ring stages (early trophozoites) are sensitive to chloroquine. In this study, the stage...http://www.malariajournal.com/content/7/1/94 |