Journal of Experimental & Clinical Assisted Reproduction - Latest articlesThe latest articles from Journal of Experimental & Clinical Assisted Reproduction (ISSN 1743-1050) published by BioMed CentralPregnancy following homologous prepubertal ovarian transplantation in the dog- April 22, 2008 In several canine models of hereditary human disease the homozygote dogs die prior to puberty, or have substantially reduced fertility. To create a clinically healthy animal that can be bred, but can also transmit the gene of interest, a model of homologous ovarian transplantation in prepubertal dogs was developed. Six dog leukocyte antigen (DLA) identical littermates underwent transplantation of ovarian cortical strips (n = 2) or the entire ovary (n = 4). Immunosuppression was maintained with..http://www.jexpclinassistreprod.com/content/5/1/1 |