Journal of Inflammation - Most viewed articlesMost viewed articles in last 30 days from Journal of Inflammation (ISSN 1476-9255) published by BioMed CentralCancer, inflammation and the AT1 and AT2 receptors- September 30, 2004 The critical role of inappropriate inflammation is becoming accepted in many diseases that affect man, including cardiovascular diseases, inflammatory and autoimmune disorders, neurodegenerative conditions, infection and cancer.This review proposes that cancer up-regulates the angiotensin II type 1 (AT1) receptor through systemic oxidative stress and hypoxia mechanisms, thereby triggering chronic inflammatory processes to remodel surrounding tissue and subdue the immune system. Based on current.http://www.journal-inflammation.com/content/1/1/3 |