Journal of Inflammation - Latest articlesThe latest articles from Journal of Inflammation (ISSN 1476-9255) published by BioMed CentralDetection of inflammatory bowel disease by proton magnetic resonance spectroscopy (1H MRS) using an animal model- November 26, 2007 Background: The aim of this study was to analyze the potential of proton magnetic resonance spectroscopy (1H MRS) in diagnosing early inflammatory bowel disease (IBD). Methods: Thirty male Sprague Dawley rats were fed 2% carrageenan in their diet for either 1 or 2 weeks. 1H MRS was performed ex-vivo on colonic mucosal samples (n = 123) and the spectra were analyzed by a multivariate method of analysis. The results of the multivariate analysis were correlated with histological analysis performed.http://www.journal-inflammation.com/content/4/1/24 |