Retrovirology - Latest articlesThe latest articles from Retrovirology (ISSN 1742-4690) published by BioMed CentralTrypanosoma cruzi (Chagas' disease agent) reduces HIV-1 replication in human placenta- July 1, 2008 Background: Several factors determine the risk of HIV mother-to-child transmission (MTCT), such as coinfections in placentas from HIV-1 positive mothers with other pathogens. Chagas' disease is one of the most endemic zoonoses in Latin America, caused by the protozoan Trypanosoma cruzi. The purpose of the study was to determine whether T. cruzi modifies HIV infection of the placenta at the tissue or cellular level. Results: Simple and double infections were carried out on a placental...http://www.retrovirology.com/content/5/1/53 |