Journal of Biology - Most viewed articlesMost viewed articles in last 30 days from Journal of Biology (ISSN 1475-4924) published by BioMed CentralGrowth control of the eukaryote cell: a systems biology study in yeast- April 30, 2007 Background: Cell growth underlies many key cellular and developmental processes, yet a limited number of studies have been carried out on cell-growth regulation. Comprehensive studies at the transcriptional, proteomic and metabolic levels under defined controlled conditions are currently lacking. Results: Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the...http://jbiol.com/content/6/2/4 |