BMC Pharmacology - Latest articlesThe latest articles from BMC Pharmacology (ISSN 1471-2210) published by BioMed CentralAntidepressant drugs modulate growth factors in cultured cells- March 4, 2008 Background: Different classes of antidepressant drugs are used as a treatment for depression by activating the catecholinergic system. In addition, depression has been associated with decrease of growth factors, which causes insufficient axonal sprouting and reduced neuronal damage repair. In this study, antidepressant treatments are analyzed in a cell culture system, to study the modulation of growth factors. Results: We quantified the transcription of several growth factors in three cell...http://www.biomedcentral.com/1471-2210/8/6 A global view of drug-therapy interactions- March 4, 2008 Background: Network science is already making an impact on the study of complex systems and offers a promising variety of tools to understand their formation and evolution in many disparate fields from technological networks to biological systems. Even though new high-throughput technologies have rapidly been generating large amounts of genomic data, drug design has not followed the same development, and it is still complicated and expensive to develop new single-target drugs. Nevertheless,...http://www.biomedcentral.com/1471-2210/8/5 |