Proceedings of the National Academy of Sciences current issueProceedings of the National Academy of Sciences RSS feed -- current issueerrata Correction for Kyrylyuk and van der Schoot, Continuum percolation of carbon nanotubes in polymeric and colloidal media- August 12, 2008http://www.pnas.org/cgi/content/short/105/32/11451?rss=1 Biophysics Capillarity-like growth of protein folding nuclei- August 12, 2008 <p>A full structural description of transition state ensembles in protein folding includes the specificity of the ordered residues composing the...http://www.pnas.org/cgi/content/short/105/32/11164?rss=1 Microbiology Effects of colonization, luminescence, and autoinducer on host transcription during development of the squid-vibrio association- August 12, 2008 The light–organ symbiosis between the squid Euprymna scolopes and the luminous bacterium Vibrio fischeri offers the opportunity to decipher the...http://www.pnas.org/cgi/content/short/105/32/11323?rss=1 Biophysics Conserved residues modulate copper release in human copper chaperone Atox1- August 12, 2008 <p>It is unclear how the human copper (Cu) chaperone Atox1 delivers Cu to metal-binding domains of Wilson and Menkes disease...http://www.pnas.org/cgi/content/short/105/32/11158?rss=1 Medical_Sciences An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes- August 12, 2008 <p>Recombinant immunotoxins are hybrid proteins composed of an Fv that binds to a tumor antigen fused to a bacterial or...http://www.pnas.org/cgi/content/short/105/32/11311?rss=1 Biophysics Single molecule force spectroscopy reveals engineered metal chelation is a general approach to enhance mechanical stability of proteins- August 12, 2008 <p>Significant mechanical stability is an essential feature shared by many elastomeric proteins, which function as molecular springs in a wide...http://www.pnas.org/cgi/content/short/105/32/11152?rss=1 Medical_Sciences Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease- August 12, 2008 <p>Telomere dysfunction limits the proliferative capacity of human cells by activation of DNA damage responses, inducing senescence or apoptosis. In...http://www.pnas.org/cgi/content/short/105/32/11299?rss=1 Biophysics Influence of nonlinear electrostatics on transfer energies between liquid phases: Charge burial is far less expensive than Born model- August 12, 2008 <p>The widely used Born model describes the electrostatic response of continuous media using static dielectric constants. However, when applied to...http://www.pnas.org/cgi/content/short/105/32/11146?rss=1 Immunology Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population- August 12, 2008 <p>NKT cell subsets can be divided based on CD4 and NK1.1 expression and tissue of origin, but the developmental and...http://www.pnas.org/cgi/content/short/105/32/11287?rss=1 Biochemistry Extracellular loop C of NPC1L1 is important for binding to ezetimibe- August 12, 2008 Niemann–Pick C1-like protein (NPC1L1) mediates the absorption of dietary cholesterol in the proximal region of the intestine, a process that...http://www.pnas.org/cgi/content/short/105/32/11140?rss=1 |