Journal of Inflammation - Most viewed articlesMost viewed articles in last 30 days from Journal of Inflammation (ISSN 1476-9255) published by BioMed CentralTopical anti-inflammatory activity of Polygonum cuspidatum extract in the TPA model of mouse ear inflammation- February 8, 2008 Background: This study tested the ability of a characterized extract of Polygonum cuspidatum (PCE) to inhibit mouse ear inflammation in response to topical application of 12-O-tetradecanoylphorbol-13-acetate (TPA). Methods: A 50% (wt:vol) ethanolic solution of commercial 200:1 PCE was applied to both ears of female Swiss mice (n = 8) at 0.075, 0.15, 0.3, 1.25 and 2.5 mgear 30 min after TPA administration (2 gear). For comparison, 3 other groups were treated with TPA and either 1) the vehicle...http://www.journal-inflammation.com/content/5/1/1 |